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>   首页   >   产品   >   蛋白产品   >   生长因子   >   fgf   >   FGF-17   

FGF-17

     
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Product Information
Primary Accession O60258
Species Human
Sequence Thr23-Thr216, expressed with an N-terminal Met
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level < 0.2 EU/ µg of protein by gel clotting method
Biological Activity ED50 < 0.5 ng/ml, measured by the cell proliferation assay using Balb/c3T3 cells, corresponding to a specific activity of > 2.0 × 106 units/mg.
Expression System E. coli
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 µg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Additional Information
Gene ID 8822
Other Names Fibroblast growth factor 17, FGF-17, FGF17
Target Background Fibroblast Growth Factor-17 (FGF-17) is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play multiple roles in biological functions, including angiogenesis, mitogenesis, cell differentiation and wound repair. FGF-17 plays an important role in organizing and inducing specific patterning at the midbrain/hindbrain junction. FGF-17 is also expressed in the hindgut, parts of thedeveloping skeleton, tail bud, major arteries, and heart. FGF-17 signals through hFGFR1c, 2c, 3c, and 4. FGF-17 signals induce patterning of the embryonic brain.
Protein Information
Name FGF17
Function Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
Cellular Location Secreted.
Tissue Location Preferentially expressed in the embryonic brain.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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