Spike protein S1

Product Information
Primary Accession	P0DTC2
Species	SARS-CoV-2
Sequence	Val16-Arg685
Purity	> 90% as analyzed by SDS-PAGE
Endotoxin Level	< 0.2 EU/ µg of protein by gel clotting method
Biological Activity	SARS-CoV-2 Spike protein (S1) can bind with Human ACE2 in functional ELISA assay.
Expression System	293 Cells
Theoretical Molecular Weight	79 kDa
Formulation	Supplied as a solution in PBS pH 7.2 containing 10% glycerol.
Storage & Stability	Upon receiving, this product remains stable for up to 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.

Additional Information
Other Names	Spike glycoprotein {ECO:0000255\|HAMAP-Rule:MF_04099}, S glycoprotein {ECO:0000255\|HAMAP-Rule:MF_04099}, E2 {ECO:0000255\|HAMAP-Rule:MF_04099}, Peplomer protein {ECO:0000255\|HAMAP-Rule:MF_04099}, Spike protein S1 {ECO:0000255\|HAMAP-Rule:MF_04099}, Spike protein S2 {ECO:0000255\|HAMAP-Rule:MF_04099}, Spike protein S2' {ECO:0000255\|HAMAP-Rule:MF_04099}, S {ECO:0000255\|HAMAP-Rule:MF_04099}
Target Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. S protein plays an important role in the induction of neutralizing antibodies and T-cell responses, as well as protective immunity.