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>   首页   >   产品   >   Galectin-9/LGALS9   

Galectin-9/LGALS9

     
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Product Information
Primary Accession Q3B8N1-2
Species Human
Sequence Met1-Thr323
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level ≤ 1 EU/ µg of protein by LAL method
Expression System Human Cells
Formulation Lyophilized from a 0.2 µm filtered solution in 50 mM MOPS, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, 5% Trehalose, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 µg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4-7°C and up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles.
Additional Information
Target Background Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Protein Information
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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