癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GMFB
- 产品详情
- 实验流程
| Primary Accession | P60983 |
|---|---|
| Species | Human |
| Sequence | Met1-His142 |
| Purity | > 95% as analyzed by SDS-PAGE |
| Endotoxin Level | < 1 EU/ µg of protein by LAL method |
| Expression System | E. coli |
| Formulation | Lyophilized from a 0.2 µm filtered solution in 20 mM Tris, 200 mM NaCl, pH 8.0. |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 µg/ml. |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4-7°C and up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles. |
| Gene ID | 2764 |
|---|---|
| Other Names | Glia maturation factor beta, GMF-beta, GMFB |
| Target Background | Glia maturation factor beta (GMFB) contains an ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis, and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF. |
| Name | GMFB |
|---|---|
| Function | This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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