癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CLDN18.2
- 产品详情
- 实验流程
| Primary Accession | P56856-2 |
|---|---|
| Species | Human |
| Sequence | Full length |
| Purity | ≥ 75% as analyzed by SDS-PAGE |
| Endotoxin Level | ≤ 0.2 EU/ µg of protein by gel clotting method |
| Biological Activity | Immobilized anti Claudin 18.2 antibody at 1 µg/ml (100 µl/Well). Dose response curve for CLDN18.2, hFc, Human with the EC50 of 17.60 ng/ml determined by ELISA. |
| Expression System | 293 Cells |
| Formulation | Supplied as a solution in 20 mM PB, 500 mM NaCl, 10% glycerol, 0.025% DDM, 0.005% CHS, pH 7.0. |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Avoid repeated freeze-thaw cycles. |
| Target Background | Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. The Expression of Isoform A2 (CLDN18.2) is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level). CLDN18.2 is founded to be abundant in gastric tumors, Experimental antibody IMAB362 targets Claudin 18.2 to help treat gastric cancers. |
|---|
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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