癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Prostatic Acid Phosphatase ACPP Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, ICC, IP |
|---|---|
| Primary Accession | P15309 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Prostatic Acid Phosphatase ACPP Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human. |
| Gene ID | 55 |
|---|---|
| Other Names | Prostatic acid phosphatase, PAP, 3.1.3.2, 5'-nucleotidase, 5'-NT, 3.1.3.5, Ecto-5'-nucleotidase, Protein tyrosine phosphatase ACP3, 3.1.3.48, Thiamine monophosphatase, TMPase, PAPf39, ACP3 (HGNC:125), ACPP |
| Calculated MW | 44566 Da |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 |
| Source | Eukaryota |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AFFB-1 |
| Immunogen | A synthesized peptide derived from human PAP ( prostatic acid phosphatase) |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ACP3 (HGNC:125) |
|---|---|
| Synonyms | ACPP |
| Function | A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins (PubMed:10506173, PubMed:15280042, PubMed:20498373, PubMed:9584846, PubMed:8132635). Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (PubMed:10506173, PubMed:15280042). |
| Cellular Location | [Isoform 1]: Secreted |
| Tissue Location | Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Low expression in prostate carcinoma cells and tissues |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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