癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Phospho CREB (Ser129) Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC |
|---|---|
| Primary Accession | P16220 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Calculated MW | 35136 Da |
| Gene ID | 1385 |
|---|---|
| Positive Control | WB: RAW264.7 cell lysate; IHC: human breast cancer tissue; IF: RAW264.7 cells |
| Application & Usage | WB; 1:500 – 1:2000, IH; 1:100 – 1:200, IF/IC; 1:100 – 1:500 |
| Other Names | Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1 |
| Target/Specificity | CREB1 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Handling | The antibody solution should be gently mixed before use |
| Reconstitution & Storage | -20°C |
| Background Descriptions | |
| Precautions | Phospho CREB (Ser129) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CREB1 |
|---|---|
| Function | Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters (By similarity). Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation (PubMed:14536081). Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity). Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ABV11953
Size:
100 µl
Price:
¥ 3,900.00
替代产品:
