CD68

Rabbit Monoclonal antibody(Mab)

Immunohistochemical analysis of formalin-fixed and paraffin-embedded human tonsil tissue was performed with CD68 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human lung carcinoma tissue was performed with CD68 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human tonsil tissue was performed with CD68 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human appendix tissue was performed with CD68 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human tonsil tissue was performed with CD68 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human tonsil tissue was performed with CD68 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	IHC-P
Primary Accession	P34810
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Clone Names	186B1E8
Calculated MW	37408 Da

Additional Information
Gene ID	968
Gene Name	CD68
Other Names	Macrosialin, Gp110, CD68, CD68
Dilution	IHC-P~~Pre-diluted Ready-To-Use (RTU)
Storage	Maintain refrigerated at 2-8°C.
Precautions	CD68 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name	CD68
Function	Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Cellular Location	[Isoform Short]: Cell membrane; Single-pass type I membrane protein
Tissue Location	Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.