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Arginase-1

Rabbit Monoclonal Antibody (Mab)

     
  • 14 - Arginase-1 AD80436
    Immunohistochemical analysis of formalin-fixed and paraffin-embedded human liver carcinoma tissue was performed with Arginase-1 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
  • 14 - Arginase-1 AD80436
    Immunohistochemical analysis of formalin-fixed and paraffin-embedded human liver tissue was performed with Arginase-1 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
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Product Information
Primary Accession P05089
Reactivity Human
Host Rabbit
Calculated MW 34735 Da
Additional Information
Gene ID 383
Gene Name ARG1
Other Names Arginase-1, 3.5.3.1, Liver-type arginase, Type I arginase, ARG1
StorageMaintain refrigerated at 2-8°C.
Precautions Arginase-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name ARG1
Function Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
Cellular Location Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957)
Tissue Location Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409)
Research Areas
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