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>   首页   >   产品   >   免疫组化   >   免疫组化抗体   >   VISTA抗体试剂(免疫组织化学)   

VISTA抗体试剂(免疫组织化学)

Rabbit Monoclonal antibody(Mab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession Q9H7M9
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names 957B1D3
Calculated MW 33908 Da
Additional Information
Gene ID 64115
Other Names V-type immunoglobulin domain-containing suppressor of T-cell activation, Platelet receptor Gi24 {ECO:0000303|Ref.1}, Stress-induced secreted protein-1 {ECO:0000303|Ref.2}, Sisp-1 {ECO:0000303|Ref.2}, V-set domain-containing immunoregulatory receptor, VSIR (HGNC:30085)
Dilution IHC-P~~N/A
StorageMaintain refrigerated at 2-8°C.
Protein Information
Name VSIR (HGNC:30085)
Function Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14- mediated MMP2 activation (PubMed:20666777).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed in spleen. Detected on a number of myeloid cells including CD11b monocytes, CD66b+ neutrophils, at low levels on CD4+ and CD8+ T-cells, and in a subset of NK cells. Not detected on B cells (at protein level). Expressed at high levels in placenta, spleen, plasma blood leukocytes, and lung. Expressed at moderate levels in lymph node, bone marrow, fat, uterus, and trachea Has low expression levels in other tissues
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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