KD-Validated Anti-Synaptosome Associated Protein 29 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application
| WB, FC, ICC |
|---|---|
| Primary Accession | O95721 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB1855 |
| Calculated MW | 28970 Da |
| Gene Name | SNAP29 |
| Aliases | SNAP29; Synaptosome Associated Protein 29; SNAP-29; Soluble 29 KDa NSF Attachment Protein; CEDNIK; Cerebral Dysgenesis, Neuropathy, Ichthyosis And Keratoderma Syndrome; Vesicle-Membrane Fusion Protein SNAP-29; Synaptosomal-Associated Protein, 29kDa; Synaptosomal-Associated Protein 29; Synaptosomal-Associated Protein, 29kD; Synaptosome Associated Protein 29kDa |
| Immunogen | A synthesized peptide derived from human SNAP29 |
| Gene ID | 9342 |
|---|---|
| Other Names | Synaptosomal-associated protein 29 {ECO:0000312|HGNC:HGNC:11133}, SNAP-29 {ECO:0000312|HGNC:HGNC:11133}, Soluble 29 kDa NSF attachment protein {ECO:0000312|HGNC:HGNC:11133}, Vesicle-membrane fusion protein SNAP-29, SNAP29 (HGNC:11133) |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SNAP29 (HGNC:11133) |
|---|---|
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions. |
| Cellular Location | Cytoplasm. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Z2P6}; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Cell projection, cilium membrane; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic Localizes to the ciliary pocket from where the cilium protrudes |
| Tissue Location | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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