SNAP29 Antibody
Rabbit mAb
- 产品详情
- 实验流程
Application
| WB, IP |
|---|---|
| Primary Accession | O95721 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Other Names | CEDNIK; SNAP29; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 28970 Da |
| Dilution | WB 1:500~1:2000 IP 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human SNAP29 |
| Description | Involved in multiple membrane trafficking steps. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | SNAP29 (HGNC:11133) |
|---|---|
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions. |
| Cellular Location | Cytoplasm. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Z2P6}; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Cell projection, cilium membrane; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic Localizes to the ciliary pocket from where the cilium protrudes |
| Tissue Location | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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