癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-CDCA8 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q53HL2 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB6600 |
| Calculated MW | 31323 Da |
| Gene Name | CDCA8 |
| Aliases | CDCA8; Cell Division Cycle Associated 8; Borealin; MESRGP; DasraB; BOR; Pluripotent Embryonic Stem Cell-Related Gene 3 Protein; Cell Division Cycle-Associated Protein 8; FLJ12042; HDasra-B; Dasra-B; Dasra B; PESCRG3 |
| Immunogen | Recombinant protein of human CDCA8 |
| Gene ID | 55143 |
|---|---|
| Other Names | Borealin, Cell division cycle-associated protein 8, Dasra-B, hDasra-B, Pluripotent embryonic stem cell-related gene 3 protein, CDCA8, PESCRG3 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CDCA8 |
|---|---|
| Synonyms | PESCRG3 |
| Function | Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. |
| Cellular Location | Nucleus, nucleolus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis Colocalizes with SENP3 in the nucleolus in interphase cells |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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