癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-EPHX1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P07099 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2b |
| Clone Names | 24GB8225 |
| Calculated MW | 52949 Da |
| Gene Name | EPHX1 |
| Aliases | EPHX1; Epoxide Hydrolase 1; EPHX; Epoxide Hydrolase 1, Microsomal (Xenobiotic); Epoxide Hydratase; EPOX; MEH; Epoxide Hydrolase 1 Microsomal; Microsomal Epoxide Hydrolase; EC 3.3.2.9; HYL1 |
| Immunogen | Recombinant protein of human EPHX1 |
| Gene ID | 2052 |
|---|---|
| Other Names | Epoxide hydrolase 1, 3.3.2.9, EPHX1 (HGNC:3401), EPHX, EPOX |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | EPHX1 (HGNC:3401) |
|---|---|
| Synonyms | EPHX, EPOX |
| Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids (PubMed:22798687). Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol (PubMed:24958911). Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity). |
| Cellular Location | Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P07687}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:P07687} |
| Tissue Location | Found in liver.. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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