癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-SELENBP1 Mouse Monoclonal Antibody
Mouse monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q13228 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 24GB13995 |
| Calculated MW | 52391 Da |
| Gene Name | SELENBP1 |
| Aliases | SELENBP1; Selenium Binding Protein 1; Methanethiol Oxidase; HSBP; LPSB; 56 KDa Selenium-Binding Protein; HSP56; SBP56; SP56; MTO; Epididymis Secretory Sperm Binding Protein Li 134P; Selenium-Binding Protein 1; HEL-S-134P; EC 1.8.3.4; EHMTO; SBP |
| Immunogen | Recombinant protein of human SELENB1 |
| Gene ID | 8991 |
|---|---|
| Other Names | Methanethiol oxidase, MTO, 1.8.3.4, 56 kDa selenium-binding protein, SBP56, SP56, Selenium-binding protein 1, SELENBP1, SBP |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SELENBP1 |
|---|---|
| Synonyms | SBP |
| Function | Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (PubMed:29255262). Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity). |
| Cellular Location | Nucleus. Cytoplasm, cytosol Membrane {ECO:0000250|UniProtKB:Q8VIF7}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8VIF7}. Note=May associate with Golgi membrane (By similarity). May associate with the membrane of autophagosomes (By similarity). {ECO:0000250|UniProtKB:Q8VIF7} |
| Tissue Location | Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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