癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-RALY Mouse Oligoclonal Antibody
Mouse oligoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9UKM9 |
| Reactivity | Human |
| Clonality | Oligoclonal |
| Isotype | Mouse IgG |
| Calculated MW | 32463 Da |
| Gene Name | RALY |
| Aliases | RALY; RALY Heterogeneous Nuclear Ribonucleoprotein; HNRPCL2; P542; RNA-Binding Protein (Autoantigenic, HnRNP-Associated With Lethal Yellow); HnRNP Associated With Lethal Yellow Protein Homolog; Heterogeneous Nuclear Ribonucleoprotein C-Like 2; HnRNP Core Protein C-Like 2; RNA-Binding Protein Raly; Autoantigen P542; RNA Binding Protein, Autoantigenic (HnRNP-Associated With Lethal Yellow Homolog (Mouse)); RNA Binding Protein, Autoantigenic (HnRNP-Associated With Lethal Yellow Homolog); RNA-Binding Protein (Autoantigenic) |
| Immunogen | Recombinant protein of human RALY |
| Gene ID | 22913 |
|---|---|
| Other Names | RNA-binding protein Raly, Autoantigen p542, Heterogeneous nuclear ribonucleoprotein C-like 2, hnRNP core protein C-like 2, hnRNP associated with lethal yellow protein homolog, RALY, HNRPCL2, P542 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RALY |
|---|---|
| Synonyms | HNRPCL2, P542 |
| Function | RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid- responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP) (PubMed:9376072). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q64012}. |
| Tissue Location | Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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