癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KO-Validated Anti-ALDH1A3 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P47895 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 25GB3805 |
| Calculated MW | 56108 Da |
| Gene Name | ALDH1A3 |
| Aliases | ALDH1A3; Aldehyde Dehydrogenase 1 Family Member A3; Retinaldehyde Dehydrogenase 3; RALDH3; ALDH6; Aldehyde Dehydrogenase 6; Aldehyde Dehydrogenase 1 Family, Member A3; Aldehyde Dehydrogenase Family 1 Member A3; Acetaldehyde Dehydrogenase 6; EC 1.2.1.36; EC 1.2.1; ALDH1A6; RALDH-3; RalDH3; MCOP8 |
| Immunogen | Recombinant protein of human ALDH1A3 |
| Gene ID | 220 |
|---|---|
| Other Names | Retinaldehyde dehydrogenase 3, RALDH-3, RalDH3, 1.2.1.36, Aldehyde dehydrogenase 6, Aldehyde dehydrogenase family 1 member A3, ALDH1A3, ALDH1A3, ALDH6 {ECO:0000303|PubMed:7698756} |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ALDH1A3 |
|---|---|
| Synonyms | ALDH6 {ECO:0000303|PubMed:7698756} |
| Function | Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans- 13,14-dihydroretinoate, respectively (By similarity) (PubMed:27759097). High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity (PubMed:27759097). Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions; a critical lipid in the embryonic development of the eye and the nasal region (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9JHW9}. |
| Tissue Location | Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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