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NPAS1 antibody - C-terminal region
Rabbit Polyclonal Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q99742 |
| Other Accession | Q99742, NP_002508, NM_002517 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 62702 Da |
| Gene ID | 4861 |
|---|---|
| Alias Symbol | MOP5, PASD5, bHLHe11 |
| Other Names | Neuronal PAS domain-containing protein 1, Neuronal PAS1, Basic-helix-loop-helix-PAS protein MOP5, Class E basic helix-loop-helix protein 11, bHLHe11, Member of PAS protein 5, PAS domain-containing protein 5, NPAS1, BHLHE11, MOP5, PASD5 |
| Target/Specificity | NPAS1 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-NPAS1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | NPAS1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPAS1 |
|---|---|
| Synonyms | BHLHE11, MOP5, PASD5 |
| Function | May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity). Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This is a rabbit polyclonal antibody against NPAS1. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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