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FHL2 antibody - C-terminal region
Rabbit Polyclonal Antibody
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- 背景知识
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q14192 |
| Other Accession | Q14192, NP_963849, NM_201555 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Dog, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 32193 Da |
| Gene ID | 2274 |
|---|---|
| Alias Symbol | DRAL, AAG11, FHL-2, SLIM3, SLIM-3 |
| Other Names | Four and a half LIM domains protein 2, FHL-2, LIM domain protein DRAL, Skeletal muscle LIM-protein 3, SLIM-3, FHL2, DRAL, SLIM3 |
| Target/Specificity | FHL2 is a member of LIM proteins that contain a highly conserved double zinc finger motif called the LIM domain. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-FHL2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | FHL2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FHL2 |
|---|---|
| Synonyms | DRAL, SLIM3 |
| Function | May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008). |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O35115} |
| Tissue Location | Expressed in skeletal muscle and heart. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This is a rabbit polyclonal antibody against FHL2. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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