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为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Dtx3 antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q80V91 |
| Other Accession | NM_030714, NP_109639 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37982 Da |
| Gene ID | 80904 |
|---|---|
| Alias Symbol | Deltex3, MGC106339, mg310 |
| Other Names | Probable E3 ubiquitin-protein ligase DTX3, 6.3.2.-, Protein deltex-3, Deltex3, mDTX3, Dtx3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Dtx3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Dtx3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Dtx3 |
|---|---|
| Function | Functions as an ubiquitin ligase protein, and regulates Notch signaling. By promoting the ubiquitination and subsequent degradation of target proteins, it can block activation of the Notch signaling pathway, potentially acting as a tumor suppressor in human cancers. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q8N9I9}. Nucleus {ECO:0000250|UniProtKB:Q8N9I9} |
| Tissue Location | Strongly expressed in testis and brain. Weakly expressed in kidney. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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