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PTPLAD2 antibody - middle region

Rabbit Polyclonal Antibody

     
  • 1 - PTPLAD2 antibody - middle region AI12455

    WB Suggested Anti-PTPLAD2 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: 293T cell lysate
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q5VWC8
Other Accession NM_001010915, NP_001010915
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Mouse, Rat, Chicken, Dog, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 27520 Da
Additional Information
Gene ID 401494
Alias Symbol DKFZp686F01145, DKFZp686G24132, HACD4
Other Names Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4, 4.2.1.134, 3-hydroxyacyl-CoA dehydratase 4, HACD4, Protein tyrosine phosphatase-like protein PTPLAD2, Protein-tyrosine phosphatase-like A domain-containing protein 2, PTPLAD2, HACD4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PTPLAD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPTPLAD2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HACD4 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:20920}
Function Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Highly expressed in leukocytes, and low expression in heart, spleen, kidney, and placenta.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Strausberg,R.L.,(2002)Proc.Natl.Acad.Sci.U.S.A.99(26),16899-16903ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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