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>   首页   >   产品   >   一抗   >   代谢   >   ADIPOR2 antibody - C-terminal region   

ADIPOR2 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - ADIPOR2 antibody - C-terminal region AI14577

    WB Suggested Anti-ADIPOR2 Antibody Titration: 1.0 μg/ml
    Positive Control: OVCAR-3 Whole Cell
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q86V24
Other Accession NM_024551, NP_078827
Reactivity Human, Mouse, Rat, Rabbit, Goat, Dog, Guinea Pig, Horse, Bovine
Predicted Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 43884 Da
Additional Information
Gene ID 79602
Alias Symbol ACDCR2, FLJ21432, MGC4640, PAQR2
Other Names Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ADIPOR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsADIPOR2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADIPOR2 (HGNC:24041)
Function Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein Note=Localized to the cell membrane and intracellular organelles
Tissue Location Ubiquitous (PubMed:16044242). Highly expressed in skeletal muscle, liver and placenta (PubMed:12802337). Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung (PubMed:12802337)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Tang Y.T.,et al.J. Mol. Evol. 61:372-380(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Yamauchi T.,et al.Nature 423:762-769(2003).

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