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>   首页   >   产品   >   一抗   >   癌症   >   CTSK antibody - middle region   

CTSK antibody - middle region

Rabbit Polyclonal Antibody

     
  • 1 - CTSK antibody - middle region AI14590

    WB Suggested Anti-CTSK Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Liver
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P43235
Other Accession NM_000396, NP_000387
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Goat, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Zebrafish
Host Rabbit
Clonality Polyclonal
Calculated MW 36966 Da
Additional Information
Gene ID 1513
Alias Symbol CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Other Names Cathepsin K, 3.4.22.38, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CTSK antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCTSK antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTSK
Synonyms CTSO, CTSO2
Function Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:11082042).
Cellular Location Lysosome. Secreted. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells
Tissue Location Predominantly expressed in osteoclasts (bones) (PubMed:7805878). Expressed in thyroid epithelial cells (PubMed:11082042).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Shi G.-P.,et al.FEBS Lett. 357:129-134(1995).
Inaoka T.,et al.Biochem. Biophys. Res. Commun. 206:89-96(1995).
Li Y.,et al.J. Bone Miner. Res. 10:1197-1202(1995).
Broemme D.,et al.Biol. Chem. Hoppe-Seyler 376:379-384(1995).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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