VINC Antibody - C-terminal region

Rabbit Polyclonal Antibody

Host: Rabbit
Target Name: VINC
Sample Tissue: PANC1 Whole Cell lysates
Antibody Dilution: 1.0μg/ml

Host: Rabbit
Target Name: VINC
Sample Tissue: PANC1 Whole Cell lysates
Antibody Dilution: 1.0μg/ml

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB
Primary Accession	P18206
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Calculated MW	123799 Da

Additional Information
Gene ID	7414
Alias Symbol	VCL,
Other Names	Vinculin, Metavinculin, MV, VCL
Format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage	Add 50 &mu, l of distilled water. Final Anti-VINC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Precautions	VINC Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	VCL
Function	Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Cellular Location	Cell membrane {ECO:0000250\|UniProtKB:P12003}; Peripheral membrane protein {ECO:0000250\|UniProtKB:P12003}; Cytoplasmic side {ECO:0000250\|UniProtKB:P12003}. Cell junction, adherens junction {ECO:0000250\|UniProtKB:P12003}. Cell junction, focal adhesion {ECO:0000250\|UniProtKB:P12003}. Cytoplasm, cytoskeleton {ECO:0000250\|UniProtKB:P85972}. Cell membrane, sarcolemma {ECO:0000250\|UniProtKB:Q64727}; Peripheral membrane protein {ECO:0000250\|UniProtKB:Q64727}; Cytoplasmic side {ECO:0000250\|UniProtKB:Q64727}. Cell projection, podosome {ECO:0000250\|UniProtKB:Q64727}. Note=Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions {ECO:0000250\|UniProtKB:P12003}
Tissue Location	Metavinculin is muscle-specific.

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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¥ 4,575.00

Cat# AI14610

Size:

50 µg

Price:

¥ 4,575.00

Quantity:

reduce add

Availability: 6-8 weeks

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