癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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MACROD2 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | A1Z1Q3 |
| Other Accession | NM_001033087, NP_001028259 |
| Reactivity | Human, Horse |
| Predicted | Human, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47421 Da |
| Gene ID | 140733 |
|---|---|
| Alias Symbol | C20orf133 |
| Other Names | O-acetyl-ADP-ribose deacetylase MACROD2, 3.2.2.-, 3.5.1.-, MACRO domain-containing protein 2, [Protein ADP-ribosylglutamate] hydrolase, MACROD2, C20orf133 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-MACROD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | MACROD2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MACROD2 {ECO:0000303|PubMed:23474712, ECO:0000312|HGNC:HGNC:16126} |
|---|---|
| Function | Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety (PubMed:23474712, PubMed:23474714). Inactive towards proteins bearing poly-ADP-ribose (PubMed:23474712, PubMed:23474714). Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins (PubMed:21257746). |
| Cellular Location | Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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