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MACROD2 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | A1Z1Q3 |
| Other Accession | NM_001033087, NP_001028259 |
| Reactivity | Human, Horse |
| Predicted | Human, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47421 Da |
| Gene ID | 140733 |
|---|---|
| Alias Symbol | C20orf133 |
| Other Names | O-acetyl-ADP-ribose deacetylase MACROD2, 3.2.2.-, 3.5.1.-, MACRO domain-containing protein 2, [Protein ADP-ribosylglutamate] hydrolase, MACROD2, C20orf133 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-MACROD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | MACROD2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MACROD2 {ECO:0000303|PubMed:23474712, ECO:0000312|HGNC:HGNC:16126} |
|---|---|
| Function | Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety (PubMed:23474712, PubMed:23474714). Inactive towards proteins bearing poly-ADP-ribose (PubMed:23474712, PubMed:23474714). Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins (PubMed:21257746). |
| Cellular Location | Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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