癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GPR89A Antibody - C-terminal region
Rabbit Polyclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | B7ZAQ6 |
| Other Accession | NM_016334, NP_057418 |
| Reactivity | Human, Mouse, Rat, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 52917 Da |
| Gene ID | 51463;653519 |
|---|---|
| Alias Symbol | GPHR, GPR89, SH120 |
| Other Names | Golgi pH regulator A, Protein GPR89A, Putative MAPK-activating protein PM01, Putative NF-kappa-B-activating protein 90, GPR89A, GPHRA, GPR89, SH120 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GPR89A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GPR89A Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR89A (HGNC:31984) |
|---|---|
| Synonyms | GPHRA, GPR89, SH120 |
| Function | Voltage-gated channel that enables the transfer of monoatomic anions such as iodide, chloride, bromide and fluoride which may function in counter-ion conductance and participates in Golgi acidification (PubMed:18794847). Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity). |
| Cellular Location | Golgi apparatus membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous.. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.
REFERENCES
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Corominas R.,et al.Nat. Commun. 5:3650-3650(2014).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Matsuda A.,et al.Oncogene 22:3307-3318(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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