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PMPCA Antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q10713 |
| Other Accession | NM_015160, NP_055975 |
| Reactivity | Human, Mouse, Rat, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58253 Da |
| Gene ID | 23203 |
|---|---|
| Alias Symbol | Alpha-MPP, INPP5E |
| Other Names | Mitochondrial-processing peptidase subunit alpha, 3.4.24.64, Alpha-MPP, P-55, PMPCA, INPP5E, KIAA0123, MPPA |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-PMPCA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PMPCA Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PMPCA |
|---|---|
| Synonyms | INPP5E, KIAA0123, MPPA |
| Function | Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. |
| Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:P20069}. Mitochondrion inner membrane |
| Tissue Location | Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Cleaves presequences (transit peptides) from mitochondrial protein precursors.
REFERENCES
Nagase T.,et al.DNA Res. 2:37-43(1995).
Nagase T.,et al.DNA Res. 2:167-174(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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