TMEM68 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| WB |
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Primary Accession | Q96MH6 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37425 Da |
Gene ID | 137695 |
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Other Names | Transmembrane protein 68, TMEM68 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-TMEM68 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TMEM68 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TMEM68 {ECO:0000303|PubMed:37648867, ECO:0000312|HGNC:HGNC:26510} |
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Function | Catalytic subunit of the alternative triglyceride biosynthesis pathway, which mediates formation of triacylglycerol from diacylglycerol and membrane phospholipids (PubMed:37648867). Synthesizes triacylglycerol at the expense of membrane phospholipids, such as phosphatidylcholine (PC) and its ether-linked form (ePC), thereby altering the composition of membranes (PubMed:37648867). The alternative triglyceride biosynthesis pathway is probably required to provide the energy required for rapid growth when fuel sources are limiting (PubMed:37648867). It maintains mitochondrial function during periods of extracellular lipid starvation (PubMed:37648867). Can also use acyl-CoA as donor: acts as a acyl-CoA:monoacylglycerol acyltransferase (MGAT), but also shows acyl-CoA:diacylglycerol acyltransferase (DGAT) activity (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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