癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CCDC85C Antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | A6NKD9 |
| Other Accession | NM_001144995, NP_001138467 |
| Reactivity | Human, Mouse, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45210 Da |
| Gene ID | 317762 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 85C, CCDC85C |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-CCDC85C antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CCDC85C Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCDC85C |
|---|---|
| Function | May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (Probable). May play an important role in cortical development, especially in the maintenance of radial glia (By similarity). |
| Cellular Location | Cell junction, tight junction {ECO:0000250|UniProtKB:E9Q6B2}. Cell junction, adherens junction. Note=Localizes to the apical junction of radial glia in the wall of lateral ventricles of the developing brain Colocalizes with TJP1 on the meshwork-like structure of adherens junctions on the lateral ventricles wall {ECO:0000250|UniProtKB:E9Q6B2} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
May play an important role in cortical development, especially in the maintenance of radial glia.
REFERENCES
Heilig R.,et al.Nature 421:601-607(2003).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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