Anti-TSPO / PBR Antibody

Rabbit Anti Mouse Polyclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P
Primary Accession	P30536
Predicted	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Calculated MW	18828 Da
Concentration (mg/ml)	0.2 mg/ml

Additional Information
Gene ID	706
Alias Symbol	TSPO
Other Names	TSPO, BZRP, BPBS, IBP, MBR, MDRC, PBR, PBRS, PBS, PKBS, PTBR, Pk18, Translocator protein, Translocator protein (18kDa)
Reconstitution & Storage	Affinity purified
Precautions	Anti-TSPO / PBR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	TSPO
Synonyms	BZRP, MBR
Function	Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral- type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678).
Cellular Location	Mitochondrion membrane; Multi-pass membrane protein
Tissue Location	Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.