癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-VAMP4 / VAMP-4 Antibody (aa1-50)
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P, IF, E |
|---|---|
| Primary Accession | O75379 |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 16397 Da |
| Gene ID | 8674 |
|---|---|
| Alias Symbol | VAMP4 |
| Other Names | VAMP4, VAMP-4, VAMP24 |
| Target/Specificity | VAMP4 Antibody detects endogenous levels of total VAMP4 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-VAMP4 / VAMP-4 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | VAMP4 (HGNC:12645) |
|---|---|
| Function | SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) are essential proteins for intracellular membrane fusion. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four-helix bundle whose assembly releases energy that drives membrane fusion. The core SNARE complex typically consists of four alpha-helical domains, three from target membrane SNAREs (t-SNAREs) and one from a vesicle SNARE (v- SNARE) (PubMed:10036234). VAMP4 is a v-SNARE that functions in vesicle fusion with the plasma membrane. In skeletal muscle satellite cells, VAMP4 cooperates with its cognate SNAREs STX11 and SNAP23 to facilitate CD36 vesicular transport from endosomes to the plasma membrane, an essential step in muscle regeneration (By similarity). |
| Cellular Location | Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:O70480}; Single-pass type IV membrane protein. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17947
Size:
100 µl
Price:
¥ 4,923.00
替代产品:
