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>   首页   >   产品   >   一抗   >   心血管   >   Anti-TFB1 / GTF2H1 Antibody (aa32-81)   

Anti-TFB1 / GTF2H1 Antibody (aa32-81)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P32780
Predicted Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 62032 Da
Additional Information
Gene ID 2965
Alias Symbol GTF2H1
Other Names GTF2H1, BTF2, BTF2 p62, p62, TFB1, TFIIH
Target/Specificity TF2H1 Antibodyantibody detects endogenous levels of TF2H1.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-TFB1 / GTF2H1 Antibody (aa32-81) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name GTF2H1 (HGNC:4655)
Synonyms BTF2
Function Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Cellular Location Nucleus.
Research Areas
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