Anti-MECP2 Antibody
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application
| WB, IHC-P |
|---|---|
| Primary Accession | P51608 |
| Predicted | Human, Mouse, Rat, Monkey, Chimpanzee, Bovine, Horse, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 52441 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 4204 |
|---|---|
| Alias Symbol | MECP2 |
| Other Names | MECP2, AUTSX3, Methyl-CpG-binding protein 2, MRX16, MRX79, MRXSL, RTT, RTS, MeCp-2 protein, RS, MRXS13, PPMX |
| Target/Specificity | The antibody detects methyl CpG binding protein 2 (MeCP2) from human, mouse and rat cells and tissues. It has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~56 kD protein representing MeCP2 from AtT20 ce ... |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-MECP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MECP2 |
|---|---|
| Function | Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9Z2D6}. Note=Colocalized with methyl-CpG in the genome. Colocalized with TBL1X to the heterochromatin foci. |
| Tissue Location | Present in all adult somatic tissues tested. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18280
Size:
50 µg
Price:
¥ 4,380.00
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