Anti-MASP2 / MASP-2 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application
| WB, IHC-P |
|---|---|
| Primary Accession | O00187 |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 75702 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 10747 |
|---|---|
| Alias Symbol | MASP2 |
| Other Names | MASP2, MASP1P1, MASP2-PEN, Small MBL-associated protein, MAP19, MASP-2, SMAP |
| Target/Specificity | Recognizes endogenous levels of MASP2 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-MASP2 / MASP-2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MASP2 {ECO:0000303|PubMed:9087411, ECO:0000312|HGNC:HGNC:6902} |
|---|---|
| Function | Precursor of a serum protease that activates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system (PubMed:11527969, PubMed:22691502). The lectin complement system is activated following association of lectins, such as MBL2, FCN1, FCN2 or FCN3, to carbohydrates on the pathogen surface (PubMed:22691502, PubMed:22966085). MASP2 is cleaved and activated by MASP1 in response to lectin-binding to pathogen carbohydrates (PubMed:10946292, PubMed:22949645, PubMed:22966085, PubMed:9087411). Can activate prothrombin to thrombin (PubMed:39924859). |
| Cellular Location | Secreted. |
| Tissue Location | Plasma.. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18435
Size:
100 µl
Price:
¥ 4,380.00
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