Anti-MASP2 Reference Antibody (narsoplimab)

Recombinant Antibody

Anti-MASP2 Reference Antibody (narsoplimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
The purity of Anti-MASP2 Reference Antibody (narsoplimab)is more than 98.94% ,determined by SEC-HPLC.
Immobilized human MASP 2A His at 2 µg/mL can bind Anti-MASP2 Reference Antibody (narsoplimab)，EC50=0.006278 µg/mL
C5b-C9 of the MBL pathway can be completely inhibited by Anti-MASP2 Reference Antibody (narsoplimab) with an IC50 of 0.7337 µg/mL.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	FC, Kinetics, Animal Model
Primary Accession	O00187
Reactivity	Human, Mouse, Rat
Clonality	Monoclonal
Isotype	IgG4
Calculated MW	75702 Da

Additional Information
Target/Specificity	MASP2
Endotoxin	< 0.001EU/ µg,determined by LAL method.
Conjugation	Unconjugated
Expression system	CHO Cell
Format	Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.

Protein Information
Name	MASP2
Function	Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Cellular Location	Secreted.
Tissue Location	Plasma.

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

Application Protocols

Provided below are standard protocols that you may find useful for product applications.