Anti-CNDP2 Antibody (aa2-475)

Rabbit Anti Human Polyclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	IHC-P, E
Primary Accession	Q96KP4
Predicted	Human
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Calculated MW	52878 Da

Additional Information
Gene ID	55748
Alias Symbol	CNDP2
Other Names	CNDP2, CN2, CPGL, CNDP dipeptidase 2, HsT2298, PEPA, Peptidase A
Target/Specificity	Human CNDP2
Reconstitution & Storage	Caprylic acid and ammonium sulfate precipitation
Precautions	Anti-CNDP2 Antibody (aa2-475) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	CNDP2 {ECO:0000303\|PubMed:25964343, ECO:0000312\|HGNC:HGNC:24437}
Function	Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue- specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism (PubMed:12473676, PubMed:19346245). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). Plays a role in the regulation of cell cycle arrest and apoptosis (PubMed:17121880, PubMed:24395568).
Cellular Location	Cytoplasm
Tissue Location	[Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568).