癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DRP-2 Antibody
Unpurified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q16555 |
| Other Accession | P47942, O08553, Q90635, O02675 |
| Reactivity | Human, Rat, Mouse |
| Predicted | Rat, Chicken, Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Clone Names | 33CT11.7.6 |
| Calculated MW | 62294 Da |
| Antigen Region | 463-492 aa |
| Gene ID | 1808 |
|---|---|
| Other Names | Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, CRMP-2, N2A3, Unc-33-like phosphoprotein 2, ULIP-2, DPYSL2, CRMP2, ULIP2 |
| Target/Specificity | This DRP-2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from human DRP-2. |
| Dilution | WB~~1:8000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DRP-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DPYSL2 |
|---|---|
| Synonyms | CRMP2, ULIP2 |
| Function | Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. |
| Cellular Location | Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane. Note=Tightly but non-covalently associated with membranes |
| Tissue Location | Ubiquitous. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
A two-stage case-control association study of the dihydropyrimidinase-like 2 gene (DPYSL2) with schizophrenia in Japanese subjects. Koide T, et al. J Hum Genet, 2010 Jul. PMID 20414250. Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity. Chae YC, et al. Cell Signal, 2009 Dec. PMID 19666111. CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity. Arimura N, et al. J Neurochem, 2009 Oct. PMID 19659462.
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