癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CRP Antibody
Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P02741 |
| Other Accession | NP_000558.2 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG3 |
| Clone Names | 506CT15.5.3 |
| Calculated MW | 25039 Da |
| Antigen Region | 8-35 aa |
| Gene ID | 1401 |
|---|---|
| Other Names | C-reactive protein, C-reactive protein(1-205), CRP, PTX1 |
| Target/Specificity | This CRP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from human CRP. |
| Dilution | WB~~1:500~1000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CRP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CRP |
|---|---|
| Synonyms | PTX1 |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Cellular Location | Secreted. |
| Tissue Location | Found in plasma. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.
REFERENCES
Brindle, E., et al. J. Immunol. Methods 362 (1-2), 112-120 (2010) :
Lim, L.S., et al. Invest. Ophthalmol. Vis. Sci. 51(9):4458-4463(2010)
Marott, S.C., et al. J. Am. Coll. Cardiol. 56(10):789-795(2010)
Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press :
Kuhlenbaeumer, G., et al. Cerebrovasc. Dis. 30(5):476-482(2010)
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