癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
WBP2 Antibody (C-term)[Knockdown Validated] 精选
Purified Mouse Monoclonal Antibody (Mab)
![1 - WBP2 Antibody (C-term)[Knockdown Validated] AM8599b](/assets/uploads/products/201607/AM8599b_WB_1.jpg)
![1 - WBP2 Antibody (C-term)[Knockdown Validated] AM8599b](/assets/uploads/products/202511/B8599b101.jpg)
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q969T9 |
| Reactivity | Human, Mouse |
| Predicted | Rat, Bovine, Canine, Chicken |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 |
| Clone Names | 932CT1.3.7 |
| Calculated MW | 28087 Da |
| Gene ID | 23558 |
|---|---|
| Other Names | WW domain-binding protein 2, WBP-2, WBP2 |
| Target/Specificity | This WBP2 antibody is generated from a mouse immunized with a recombinant protein between 1-261 amino acids from the C-terminal region of human WBP2. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WBP2 Antibody (C-term)[Knockdown Validated] is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | WBP2 (HGNC:12738) |
|---|---|
| Function | Acts as a transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation (PubMed:16772533). In presence of estrogen, binds to ESR1-responsive promoters (PubMed:16772533). Synergizes with YAP1 to enhance PGR activity (PubMed:16772533). Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus when phosphorylated. |
| Tissue Location | Ubiquitous. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Chen H.I.,et al.J. Biol. Chem. 272:17070-17077(1997).
Pirozzi G.,et al.J. Biol. Chem. 272:14611-14616(1997).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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¥ 1,250.00
Cat# AM8599b
