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PNOC Antibody (Center)

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - PNOC Antibody (Center) AM8712b
    Anti-PNOC Antibody (Center) at 1:8000 dilution + PNOC recombinant protein Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 18 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q13519
Reactivity Human
Predicted Human
Host Mouse
Clonality monoclonal
Isotype IgG2b,κ
Clone Names 2133CT1268.37.7
Calculated MW 20295 Da
Additional Information
Gene ID 5368
Other Names Prepronociceptin, Nocistatin, Nociceptin, Orphanin FQ, PPNOC, Orphanin FQ2, PNOC, OFQ
Target/Specificity This PNOC antibody is generated from a mouse immunized with a recombinant protein from human PNOC.
Dilution WB~~1:8000
E~~Use at an assay dependent concentration.
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPNOC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PNOC
Synonyms OFQ
Function [Nociceptin]: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
Cellular Location Secreted.
Tissue Location Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.

REFERENCES

Mollereau C.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:8666-8670(1996).
Nothacker H.-P.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:8677-8682(1996).
Fiset M.E.,et al.Biochemistry 42:10498-10505(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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