癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LCN1 Antibody
Purified Mouse Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | P31025 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 10B10 |
| Isotype | IgG1 |
| Calculated MW | 19250 Da |
| Description | LCN1: lipocalin 1 (tear prealbumin), also known as TP, PMFA, VEGP. Entrez Protein: NP_002288. The protein belongs to the lipocalin family. Lipocalins are a group of extracellular proteins that are able to bind lipophiles by enclosure within their structures to minimize solvent contact. This protein may bind hydrophobic ligands and inhibit cysteine proteinases. It may also play a role in taste reception and could be necessary for the concentration and delivery of sapid molecules in the gustatory system. |
| Immunogen | Purified recombinant fragment of LCN1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 3933 |
|---|---|
| Other Names | Lipocalin-1, Tear lipocalin, Tlc, Tear prealbumin, TP, Von Ebner gland protein, VEG protein, LCN1, VEGP |
| Dilution | WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 ICC~~N/A E~~N/A |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LCN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LCN1 |
|---|---|
| Synonyms | VEGP |
| Function | Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. |
| Cellular Location | Secreted. |
| Tissue Location | Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1. Adv Exp Med Biol. 2002;506(Pt A):555-65. 2. J Autoimmun. 2005 Nov;25(3):229-34.
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