癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PPM1G Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O15355 |
| Other Accession | O15355 |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 59272 Da |
| Physical State | Liquid |
| Immunogen | A synthesized peptide derived from human PPM1G |
| Epitope Specificity | 301-450 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| SIMILARITY | Belongs to the PP2C family. |
| Post-translational modifications | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. |
| Gene ID | 5496 |
|---|---|
| Other Names | PPM1G_HUMAN; PPM1G; Protein phosphatase 1C; Protein phosphatase 2C isoform gamma (PP2C-gamma); Protein phosphatase magnesium-dependent 1 gamma; 3.1.3.16; PPM1C; PP2CG; PP2CGAMMA; PPP2CG; protein phosphatase, Mg2+/Mn2+ dependent 1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase, Mg2+/Mn2+ dependent, 1G; PP2C, gamma; protein phosphatase 2C, gamma isoform |
| Dilution | WB=1:500-2000,IHC-P=1:100-200,IHC-F=1:100-200,IF=1:50-200,Flow-Cyt=1:50-100 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PPM1G |
|---|---|
| Synonyms | PPM1C |
| Cellular Location | Cytoplasm. Membrane; Lipid-anchor |
| Tissue Location | Widely expressed. Most abundant in testis, skeletal muscle, and heart |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP100164
