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>   首页   >   产品   >   一抗   >   细胞生物学   >   PPM1G Antibody (Center)   

PPM1G Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PPM1G Antibody (Center) AP8434b
    Western blot analysis of hPPM1G-C164 (Cat. #AP8434b) in 293 cell line lysates (35ug/lane). PPM1G (arrow) was detected using the purified Pab.
  • 1 - PPM1G Antibody (Center) AP8434b
    Western blot analysis of hPPM1G-C164 (Cat. #AP8434b) in mouse heart tissue lysates (35ug/lane). PPM1G (arrow) was detected using the purified Pab.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O15355
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 59272 Da
Antigen Region 150-180 aa
Additional Information
Gene ID 5496
Other Names Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, PPM1G, PPM1C
Target/Specificity This PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the Central region of human PPM1G.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPM1G Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPM1G
Synonyms PPM1C
Cellular Location Cytoplasm. Membrane; Lipid-anchor
Tissue Location Widely expressed. Most abundant in testis, skeletal muscle, and heart
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.

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