癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CCDC37 Antibody (N-term) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q494V2 |
| Other Accession | NP_872434.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 71117 Da |
| Antigen Region | 16-45 aa |
| Gene ID | 348807 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 37, CCDC37 |
| Target/Specificity | This CCDC37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human CCDC37. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CCDC37 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CFAP100 (HGNC:26842) |
|---|---|
| Function | Microtubule-associated protein that promotes microtubule polymerization and regulates microtubule organization (PubMed:37192300). Plays a critical role in ensuring proper epidermal development and function by regulating mitosis in keratinocytes (PubMed:40593606). Maintains spindle pole integrity during keratinocyte division through the recruitment of the microtubule glutamylase TTLL13 to spindle poles, thereby enhancing localized microtubule glutamylation (PubMed:40593606). This modification stabilizes spindle microtubules, ensuring accurate spindle assembly, faithful chromosome segregation, and efficient mitotic progression (PubMed:40593606). May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A8I4E9}. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=Localizes to microtubules |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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