癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FGL2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q14314 |
| Other Accession | NP_006673.1 |
| Reactivity | Human, Rat, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50229 Da |
| Antigen Region | 338-367 aa |
| Gene ID | 10875 |
|---|---|
| Other Names | Fibroleukin, Fibrinogen-like protein 2, pT49, FGL2 |
| Target/Specificity | This FGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-367 amino acids from the C-terminal region of human FGL2. |
| Dilution | WB~~1:2000 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FGL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FGL2 |
|---|---|
| Function | May play a role in physiologic lymphocyte functions at mucosal sites. |
| Cellular Location | Secreted. |
| Tissue Location | Constitutively expressed in cytotoxic T-cells. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
REFERENCES
Liu, Y., et al. Biochem. Biophys. Res. Commun. 396(2):555-561(2010)
Hsieh, Y.H., et al. Bull. Math. Biol. 72(1):122-132(2010)
Siu, K.L., et al. J. Gen. Virol. 90 (PT 9), 2107-2113 (2009) :
Han, M., et al. J. Biol. Chem. 283(47):32715-32729(2008)
Su, K., et al. World J. Gastroenterol. 14(39):5980-5989(2008)
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