癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IL17B Antibody (Center) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q9UHF5 |
| Other Accession | NP_055258.1 |
| Reactivity | Human, Mouse |
| Predicted | Rat, Bovine, Canine, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20437 Da |
| Antigen Region | 39-66 aa |
| Gene ID | 27190 |
|---|---|
| Other Names | Interleukin-17B, IL-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, IL17B, IL20, NIRF, ZCYTO7 |
| Target/Specificity | This IL17B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human IL17B. |
| Dilution | WB~~1:1000 IHC-P~~1:100 IF~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IL17B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | IL17B |
|---|---|
| Synonyms | IL20, NIRF, ZCYTO7 |
| Function | Stimulates the release of tumor necrosis factor alpha and IL- 1-beta from the monocytic cell line THP-1. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.
REFERENCES
Koskinen, L.L., et al. Tissue Antigens 74(5):408-416(2009)
Wang, X., et al. Ann. Otol. Rhinol. Laryngol. 115(6):450-456(2006)
Ryan, A.W., et al. Tissue Antigens 65(2):150-155(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Moore, E.E., et al. Neuromuscul. Disord. 12(2):141-150(2002)
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