DLL3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IHC-P-Leica, WB, IF, E |
---|---|
Primary Accession | Q9NYJ7 |
Other Accession | NP_058637.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 64618 Da |
Antigen Region | 545-573 aa |
Gene ID | 10683 |
---|---|
Other Names | Delta-like protein 3, Drosophila Delta homolog 3, Delta3, DLL3 |
Target/Specificity | This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 545-573 amino acids from the C-terminal region of human DLL3. |
Dilution | IHC-P-Leica~~1:500 WB~~1:2000 IF~~1:10~50 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DLL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DLL3 |
---|---|
Function | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].
REFERENCES
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Heuss, S.F., et al. Proc. Natl. Acad. Sci. U.S.A. 105(32):11212-11217(2008)
Maisenbacher, M.K., et al. Hum. Genet. 116(5):416-419(2005)
Whittock, N.V., et al. Clin. Genet. 66(1):67-72(2004)
Bonafe, L., et al. Clin. Genet. 64(1):28-35(2003)

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