BEND6 Antibody (C-term) 精选

Affinity Purified Rabbit Polyclonal Antibody (Pab)

BEND6 Antibody (C-term) (Cat. #AP12587b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BEND6 antibody detected the BEND6 protein (arrow).
BEND6 Antibody (C-term) (Cat. #AP12587b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BEND6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	Q5SZJ8
Other Accession	NP_689944.2
Reactivity	Human
Predicted	Bovine, Canine, Rabbit, Chicken
Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Calculated MW	31222 Da
Antigen Region	226-254 aa

Additional Information
Gene ID	221336
Other Names	BEN domain-containing protein 6, BEND6, C6orf65
Target/Specificity	This BEND6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human BEND6.
Dilution	WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration.
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions	BEND6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name	BEND6
Synonyms	C6orf65
Function	Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis (PubMed:23571214).
Cellular Location	Nucleus {ECO:0000250\|UniProtKB:Q6PFX2}.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.