癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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ZDHHC13 Antibody (N-term) 精选
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IUH4 |
| Other Accession | Q80TN5, Q8IUH5, Q4R690, NP_061901.2 |
| Reactivity | Human |
| Predicted | Monkey, Mouse, Rat, Bovine, Canine, Rabbit, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70861 Da |
| Antigen Region | 55-83 aa |
| Gene ID | 54503 |
|---|---|
| Other Names | Palmitoyltransferase ZDHHC13, Huntingtin-interacting protein 14-related protein, HIP14-related protein, Huntingtin-interacting protein HIP3RP, Putative MAPK-activating protein PM03, Putative NF-kappa-B-activating protein 209, Zinc finger DHHC domain-containing protein 13, DHHC-13, ZDHHC13, HIP14L, HIP3RP |
| Target/Specificity | This ZDHHC13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ZDHHC13. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZDHHC13 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZDHHC13 (HGNC:18413) |
|---|---|
| Function | Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (By similarity). Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. |
| Cellular Location | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9CWU2}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9CWU2}; Multi-pass membrane protein. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles. {ECO:0000250|UniProtKB:Q9CWU2} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ZDHHC13 is palmitoyltransferase for HD and GAD2 (By similarity).It mediates Mg(2+) transport (By similarity).
REFERENCES
Goytain, A., et al. J. Biol. Chem. 283(48):33365-33374(2008)
Matsuda, A., et al. Oncogene 22(21):3307-3318(2003)
Singaraja, R.R., et al. Hum. Mol. Genet. 11(23):2815-2828(2002)
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