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>   首页   >   产品   >   一抗   >   细胞生物学   >   PRSS16 Antibody (N-term)   

PRSS16 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PRSS16 Antibody (N-term) AP16588a
    PRSS16 Antibody (N-term) (Cat. #AP16588a) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PRSS16 antibody detected the PRSS16 protein (arrow).
  • 1 - PRSS16 Antibody (N-term) AP16588a
    PRSS16 Antibody (N-term) (Cat. #AP16588a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PRSS16 antibody detected the PRSS16 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NQE7
Other Accession NP_005856.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 55049 Da
Antigen Region 52-81 aa
Additional Information
Gene ID 10279
Other Names Thymus-specific serine protease, 34--, Serine protease 16, PRSS16, TSSP
Target/Specificity This PRSS16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human PRSS16.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRSS16 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRSS16
Synonyms TSSP
Function Protease that may play a role in T-cell development.
Cellular Location Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal
Tissue Location Expressed predominantly in cortical thymic epithelial cells
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.

REFERENCES

Shi, J., et al. Nature 460(7256):753-757(2009)
Stefansson, H., et al. Nature 460(7256):744-747(2009)
Viken, M.K., et al. Genes Immun. 10(4):323-333(2009)
Lie, B.A., et al. Hum. Immunol. 68(7):592-598(2007)
Luther, C., et al. Genes Immun. 6(1):1-7(2005)

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